Beautiful shot. The focus is excellent, yet not quite overwhelming. Focused enough to see the path of the scales shape. And also, you can see if the scales are lighter on the skin or more forced in from the light or dark bordering of the spines.Each individual spine/scale is something of its own, very interesting subject to take of photo of. Im quite a fan of lizards, but this has to be one of the best shots i have seen in a long time. And it gives it a more crisp look because of the enlarged pupils i believe. And is that moisture forming at his mouth a little bit? Haha, to sum it up, very clean piece. Thank you for posting~!
Where to start? On the positive side, we've got a pretty nice depth of field which is cool to have in most cases. I also really like the texture on the chameleon. (Is it a chameleon?) On the negative side, focus is little out of hand. Even though I know it's must be tricky to get a shot of these animals just right but I would welcome crisper details and a better focus. Nothing big, though, just a side note. Did you use a tele lens?
To sum it up, I would give you 7/10 points for the photo.